Gorlin-Goltz Syndrome: The importance of Clinical Investigation and a Multidisciplinary Approach

2021 • Volume 15 • Issue 1

Andressa Bolognesi Bachesk; Silvia Natália Souza de Peder; Romulo Maciel Lustosa; Lucas Costa Nogueira & Liogi Iwaki Filho



Gorlin-Goltz Syndrome is a genetic disorder characterized by a series of clinical changes, including the presence of multiple odontogenic keratocysts and nevus basal cell carcinomas. As these lesions involve the maxillofacial region and can evolve to severe sequelae, it is essential that the dental surgeon recognize this pathology, in order to promote a correct investigation and early multidisciplinary diagnosis and treatment. The treatment for the cysts varies according to the lesion’s characteristics and location, and therefore, the request for complementary exams is essential. According to literature, the approach varies from conservative to more invasive, and several supporting therapies are mentioned. Thus, this article aims to report a case of a young patient diagnosed with Gorlin-Goltz Syndrome by a dental surgeon, who treated conservatively and interdisciplinarly, and obtained a satisfactory result. In addition, it makes a bibliographic review on this genetic condition, elucidating its therapeutic forms.

KEY WORDS: basal cell carcinoma, clinical diagnosis, combined modality therapy, Gorlin–Goltz syndrome, keratocystic odontogenic.


How to cite this article

BACHESK, A. B.; PEDER, S. N. S.; LUSTOSA, R. M.; NOGUEIRA, L. C. & IWAKI FILHO, L. Gorlin-Goltz Syndrome: The importance of clinical investigation and a multidisciplinary approach. Int. J. Odontostomat., 15(1):189-195, 2021.


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