Variation of Cardiovascular Parameters in Patients undergoing Unerupted Third Molar Surgery under Local Anesthesia Associated with Vasoconstrictor

2008 • Volume 2 • Issue 2

Cortés, C. Daniel; Chapuzzeau, L. Eduardo & Argandoña, Pozo Juan



Local anesthetics associated with vasoconstrictors agents are widely used in common dental practice and oral surgery. These inhibit the conduction of nerve impulse, generating a reversible loss of local sensitivities in relation to the site of application and may provoke hemodynamic changes, being potentially negative for those patients who have any systemic disease. The aim of this study was to determine if there are variations within cardiovascular parameters pre and post anesthesia of the inferior alveolar nerve with vasoconstrictor in patients undergoing to mandibular third molar surgery. The sample included 20 healthy patients between 17 and 24 years old, selected for mandibular third molar surgery. The procedure took place in the oral surgery’s operating rooms of the Faculty of Dentistry of the Universidad Finis Terrae. Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and heart rate (HR) were measured in 20 patients, at three different times: 1. At the time of the examination. 2. Before the anesthetic infiltration. 3. Five minutes subsequent to the infiltration (4 tubes of lidocaine 2% with epinephrine 1:100.000). The comparisons of the values between the different times within each gender were made, by means of Duncan’s multiple comparison of averages, and the comparisons between the different times and between both genders were made by means of t-student’s test. The signification level used was a = 0.05. From the comparison of the studied parameters, we found that the MAP and the DBP did not present significant changes between the studied times; the same happened with the SBP in the female group. Nevertheless, we found that in the male group, the SBP was significantly greater in third time in relation to the first time. Thus also, we found a significant difference in the HR parameter, being the average of the first time measurement smaller than the average of second time for both genders. In addition, the female group presented a significantly greater HR than the male group at the third time.

KEY WORDS: systolic blood pressure, diastolic blood pressure, mean arterial pressure, heart rate, epinephrine.


How to cite this article

CORTÉS, C. D. & CHAPPUZEAU, L. E. & ARGANDOÑA, P. J. Variation of cardiovascular parameters in patients undergoing to unerupted third molar surgery under local anesthesia associated with vasoconstrictor. Int. J. Odontostomat., 2(2):129136, 2008.


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