Update on the Diagnosis and Treatment of Ameloblastic Fibroma: Systematic Review

2023 • Volume 17 • Issue 4

Benjamín Quintana Mallea & Diego Ramírez Villalobos



Ameloblastic fibroma (AF) is a benign neoplasm with the potential for recurrence and malignant transformation that affects the maxillofacial bones. Recent cases of AF were analyzed to describe their clinical characteristics and treatment options. The objective of this study is to enhance understanding of this rare disease and provide relevant information for the diagnosis and management of patients. A literature review was conducted to identify case reports of AF published in the past 5 years. After removing duplicates, 16 studies were selected for analysis. Sociodemographic data, lesion location, clinical signs, radiographic findings, and treatment options were collected. The included studies reported cases of AF in patients aged between 4 and 21 years. There was a slight male predominance. The most common location of the lesion was the posterior mandible. The most frequent clinical signs were increased bone volume and pain. Radiographically, predominantly multilocular radiolucent lesions were found. The most common treatment was lesion enucleation. No recurrences were observed during the follow-up of the reported cases. The results align with recent literature, providing updated information on the clinical and radiographic profile of AF. Enucleation emerges as an effective treatment option. These findings contribute to accurate diagnosis and appropriate management of patients with AF, highlighting the importance of understanding the clinical characteristics of this neoplasm.

KEY WORDS: Ameloblastic fibroma, odontogenic tumor, pathology, enucleation.


How to cite this article

QUINTANA, M. B. & RAMÍREZ, V. D. Update on the diagnosis and treatment of ameloblastic fibroma: systematic review. Int. J. Odontstomat., 17(4):463-469, 2023.


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