Detection of COVID-19 (SARS-CoV-2) by Saliva: A Low-invasive Diagnostic Alternative

2020 • Volume 14 • Issue 3

Andrés Melián Rivas; Pablo Calcumil Herrera; Camila Boin Bakit & Rolando Carrasco Soto



The new coronavirus disease, also called COVID 19, is the latest infectious disease of international concern. Originating in Wuhan, China, it spread globally, resulting in the 2019-2020 pandemic and a Public Health Emergency of International Concern (ESPII) as declared by the World Health Organization (WHO). This disease usually presents with fever, cough, sore throat, respiratory distress, fatigue and general discomfort; however, asymptomatic cases have been reported. The diagnosis is made with a combination of clinical, radiological and laboratory molecular tests, where the reverse transcriptase polymerase chain reaction (RT-PCR) test has been the alternative of choice for the analysis of viral genetic material from samples taken of upper respiratory tract. COVID-19 has been reported to be transmitted person-to-person or by indirect fluids drop contact, which is of fundamental importance for clinical dental procedures and where saliva would play a critical role in the transmission of SARS-CoV-2 from human to human. For this reason, non-invasive salivary diagnoses could provide a platform for rapid, early and non-invasive detection of COVID19 infection. The objective of this review is to determine the benefits of saliva as a non-invasive sample for the diagnosis of COVID-19.

KEY WORDS: Saliva, diagnosis, COVID-19, dentistry.


How to cite this article

MELIÁN, R. A.; CALCUMIL, H. P.; BOIN, B. C. & CARRASCO, S. R. Detection of COVID-19 (SARS-CoV-2) by saliva: A low-invasive diagnostic alternative. Int. J. Odontostomat., 14(3):316-320, 2020.


PDF of the article.