Comparative Study: Oral Pathologies Prevalence in Pediatric Oncology Patients 1997 – 2007

2010 • Volume 4 • Issue 2

Rodriguez, M.; Manriquez, X.; Rojas, I. G.; Fernandez, E.; Bretahuer, U. & Sepúlveda, E.



Pediatric oncology patients frequently have oral lesions due to malignancy or as a side effect of treatment. The aim of this study was to compare the prevalence of oral pathologies in oncology patients hospitalized and treated at the Regional Hospital of Concepción, Chile, in the years 1997 and 2007. A retrospective study was carried out in 74 patients each year. Patients suffered from acute lymphoblastic leukemia, acute myeloblastic leukemia, central nervous system tumors, lymphomas and other neoplasms. General data (age, gender, oncologic disease) and presence of oral pathologies (candidiasis, mucositis post-chemotherapy, herpetic lesions and hemorrhage) were obtained from their clinical records. Data was analyzed for statistical differences. A significant reduction in the number of patients with oral pathologies was found in 2007 in comparison to 1997 (P<0.05, Fisher´s test). In addition, candidiasis and oral mucositis showed less prevalence in 2007 as compared to 1997, although no significant differences were found. For the relevance of oral pathologies in the chemotherapy it´s important to continue studies about prevention, early detection and treatment of oral pathologies.

KEY WORDS: oral pathologies, pediatric oncology patients, chemotherapy.


How to cite this article

RODRIGUEZ, M.; MANRIQUEZ, X.; ROJAS, I. G.; FERNANDEZ, E.; BRETAHUER, U. & SEPÚLVEDA, E. Comparative study: oral pathologies prevalence in pediatric oncology patients 1997- 2007. Int. J. Odontostomat., 4(2):149-156, 2010.


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