Although epigenetic processes are widely studied, no one has related them to the classical genetic processes in oral cancer etiopathogenesis. The traditional carcinogenesis and epigenetic views converge in the same molecular pathways involved in cancer development, enhancing this process. This review will approach the VEGF-C/VEGFR, HB-EGF/EGFR, Wnt /B-catenin, and cyclins molecular pathways from the genetic and epigenetic views to establish their connection during the oral cancer process.
KEY WORDS: oral neoplasms, epigenomics.
How to cite this article
TORRES, G. M.; FUENTES, P. B. & CASTRO, A. F. Oral carcinogenesis and epigenetics. Int. J. Odontostomat., 15(4):850-856, 2021.