Antimicrobial Efficacy of Portland Cement Compared to Mineral Trioxide Aggregate Against Enterococcus faecalis and Candida albicans

2022 • Volume 16 • Issue 1

Eduardo Quea Cahuana; Wiliam Ramirez Mesias; María del Carmen Manrique Coras; Silvana Anduaga Lescano; Rafael Morales Vadillo & César Félix Cayo Rojas



The aim of the experimental in vitro study was to evaluate the antimicrobial efficacy of Portland cement (CP) compared with Mineral Trioxide Aggregate (MTA) against Enterococcus faecalis (E. faecalis) and Candida albicans (C. albicans) strains at 24, 48 and 72 hours after sowing. For this, the agar diffusion technique was used. The base layer was made with Müller-Hinton Agar in which 6 mm diameter holes were made in order to contain the study cements and subsequently measure the zone of microbial inhibition around the materials using a digital vernier caliper. The Student’s t test was used to compare the difference between CP and MTA and the ANOVA analysis to evaluate the differences between the three study times. The results showed that both against E. faecalis and C. albicans, CP had a greater inhibition than MTA, these differences being statistically significant (p <0.05). When the three study times were compared for each cement, there were no significant differences (p> 0.05). Likewise, C. albicans presented higher inhibition values than E. faecalis in the two cements studied. It was concluded that CP had greater antimicrobial efficacy than MTA regardless of the time evaluated.

KEY WORDS: mineral trioxide aggregate, accelerated portland cement, Enterococcus faecalis, Candida albicans.


How to cite this article

QUEA, C. E.; RAMIREZ, M. W.; MANRIQUE, C. M. C.; ANDUAGA, L. S.; MORALES, V. R. & CAYO, R. C. F. Antimicrobial efficacy of Portland cement compared to Mineral Trioxide Aggregate against Enterococcus faecalis and Candida albicans. Int. J. Odontostomat., 16(1):13-18, 2022.


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