Effects of low vitamin D levels on dental implant treatment: a scoping review

The aim of this review was to assess low serum levels of vitamin D and its potential effects on dental implant therapy. This study identifies as a scoping review and was conducted using the PRISMA extension for scoping review. Three databases were searched up to September 2024. Low serum levels of vitamin D and dental implants were assessed in animals or humans. Five studies assessed the impact of low vitamin D levels on osseointegration, using radiographs and implant stability analysis at different time points, up to 12 months. Patients with deficient vitamin D levels (<10 ng/ml) experienced greater marginal bone loss compared to those with adequate levels (>30 ng/ml). Two studies supplemented vitamin D in deficient patients, reporting less bone loss and better implant stability. One study correlated vitamin D levels with implant stability quotient, highlighting that an increase in vitamin D significantly improved stability. Analysis in rats revealed that vitamin D deficiency significantly decreased bone-implant contact. Deficient vitamin D levels were associated with early implant loss and osseointegration failure. These results should be interpreted with caution due to the heterogeneity of the studies and the lack of clinical trials.

GARRIDO, M.; SÁEZ-PINO, M.; SEGOVIA-CHAMORRO, J. & NICCOLI-MERELLO, E. Effect of low vitamin D levels on dental implant treatment: a scoping review. Int. J. Odontostomat., 19(3):252-261, 2025.