Summary
It is currently known that dental caries is one of the most common non-communicable chronic diseases worldwide, whose etiology has been attributed to Streptococcus, with the consumption of sweeteners such as D-Tagatose being related to anticariogenic effects. The objective of this study was to analyze the effect of D-tagatose on the proliferation of oral bacteria related to carious lesions. A systematic review of original articles published between 2013 and 2023 in the databases Europe PMC, Medline (PubMed), Cochrane Central, Virtual Health Library and Scopus was carried out, using the following search strategy: ”Tagatose OR D-tagatose AND Dental Caries”. The quality of the evidence collected being analyzed with the Guidelines for critical review of qualitative studies. The search identified 79 records of which 2 met the eligibility criteria. In general, the selected articles indicate that D-Tagatose in doses between 0.1 to 10 % can inhibit both the bacterial growth of Streptococcus mutans and the production of glycosyltransferase-B related to dental biofilm. D-tagatose possibly inhibits the proliferation of oral bacteria related to caries lesions. However, new studies are needed in vivo models that seek to demonstrate these possible anticariogenic effects.
KEY WORDS: tagatose, dental caries, Streptococcus mutans, biofilms.
How to cite this article
INOSTROZA-RIVERA, V.; QUIÑILÉN-COFRÉ, F.; ANGARITA-DAVILA, L.; FUENTES-BARRIA, H.; CARRASCO-HERNÁNDEZ, M. E. & AGUILERA-EGUÍA, R. Effects of D-Tagatose on bacterial growth of the genus Streptococcus. Systematic review. Int. J. Odontostomat., 18(4):426-432, 2024.
