Hypochlorous Acid: A New Alternative as Antimicrobial Agent and For Cell Proliferation for Use in Dentistry

Gloria Inés Lafaurie; Justo Leonardo Calderón; Carlos Zaror; Lina Viviana Millán & Diana Marcela Castillo

Summary

Hypochlorous acid (HOCl) is a powerful non antibiotic antimicrobial solution used in clinical medicine for infection control and wound healing. In vivo HOCl is produced by cells of the immune system to control the pathogen during phagocytosis and has been synthesized and stabilized in the laboratory with potential prophylactic and therapeutic applications in human medicine. The antimicrobial, anti-inflammatory and cell proliferation effect make it a substance to be evaluated in other health areas. There is interest to development of new antimicrobial substances for use in oral health for the control of dental biofilm, gingival inflammation and wound healing of the oral mucosa. A review of the literature of the main effects of HOCl that support its research and use in dentistry is presented.

KEY WORDS: hypochlorous acid, HOCl, dental biofilm, wound healing.

How to cite this article

LAFAURIE, G. I.; CALDERÓN, J. L.; ZAROR, C.; MILLÁN, L. V. & CASTILLO, D. M. Hypochlorous acid: A new alternative as antimicrobial agent and for cell proliferation for use in dentistry. Int. J. Odontostomat., 9(3):475-481, 2015.