Assessment of Tumor Associated Tissue Eosinophilia (TATE) in Oral Squamous Cell Carcinoma Using Carbol Chromotrope Stain

Celestina Dawn Peter; R. Shashidara; Vanishree C. Haragannavar; Pradeep Samuel; Sudheendra Udyavara Sridhara; Aparna H Gopalkrishna; Sheela Poojary; Suhas R. Nayak & Anu Sushanth A.

Summary

Tumor related tissue eosinophilia (TATE) is a known phenomenon but its role in prognostics and correlation with size of the primary tumor is still controversial. Using a stain, like Carbol chromotrope, that targets eosinophils exclusively and vividly, offers an advantage over haematoxylin and eosin, which was used in most of the studies. Forty-nine cases of oral squamous cell carcinoma, where the TNM staging has been recorded in their history, was taken and stained with Lendrum’s carbol chromotrope. Significant difference in the eosinophil count with varying size of the tumor and a parallel increase in the number noted, with increase in size. There is a corresponding increase in the number of eosinophils infiltrating the tumor with increase in size of oral squamous cell carcinoma.

KEY WORDS: TATE, eosinophils, carbol chromotrope, oral squamous cell carcinoma.

How to cite this article

PETER, C. D.; SHASHIDARA, R; HARAGANNAVAR, V. C.; SAMUEL, P.; SRIDHARA, S. U.; GOPALKRISHNA, A. H.; POOJARY, S.; NAYAK, S. R. & SUSHANTH, A. A. Assessment of tumour associated tissue eosinophilia (TATE) in oral squamous cell carcinoma using carbol chromotrope stain. Int. J. Odontostomat., 9(1):91-95, 2015.