Osteonecrosis of the Jaws Associated with Drugs and Monoclonal Antibodies. Systematic Review of the Literature and Proposal for Prevention and Management in an Extraction Procedure

Andrea del Pilar López Riffo; Ivana de los Ángeles Ojeda González & Ingrid Tobar Gatica

Summary

The objective of this systematic review was to search for preventive and treatment measures for osteonecrosis associated with medications and monoclonal antibodies to propose a new protocol if necessary. This literature review was conducted in PubMed/MedLine, Cochrane, SciELO, and EBSCO; limiting the search from January 1, 2017 to September 22, 2022. A total of 8 articles were included. Although the greatest amount of accurate evidence was included, non-significant results were obtained. There is currently a protocol from the American Association of Oral and Maxillofacial Surgery, however, more clinical evidence is needed.

KEY WORDS: drug-associated osteonecrosis, monoclonal antibodies, extraction, prevention and treatment.

How to cite this article

LÓPEZ RIFFO, A. P.; OJEDA GONZÁLEZ, I. A. & TOBAR GATICA, I. Osteonecrosis of the jaws associated with medications and monoclonal antibodies. Systematic review of the literature and proposal for prevention and management in an extraction procedure. Int. J. Odontostomat., 18(2):141-147, 2024.