Jefferson David Melo de Matos; Leonardo Jiro Nomura Nakano; Guilherme da Rocha Scalzer Lopes; Sérgio Eberson Da Silva Mais; Adriano Baldotto Barbosa; Marco Antonio Bottino & Valdir Cabral Andrade
The present study aimed to review the literature on the main complications of antineoplastic therapies and the degree of knowledge of dental surgeons about these complications. A bibliographic search was conducted in the main health databases PUBMED (www.pubmed.gov) and Scholar Google (www.scholar.google.com.br), in which studies published from 1987 to 2023 were collected. Laboratory studies, case reports, systematic and literature reviews, which were developed in living individuals, about the main neoplastic genes and their relationship with the cells of individuals affected by neoplasms in the head and neck region, and studies on the care with this group of patients, were included. Therefore, articles that did not deal with neoplasm and the main complications of antineoplastic therapies were excluded. Neoplasm is a clonal disorder, caused by mutations, resulting from changes in the genetic structure of cells. Each healthy cell has instructions on how to grow and divide. In the presence of any error in these instructions (mutation), it can result in a diseased cell that, when proliferating, may cause a tumor. Countless knowledge has been accumulated over the years on the main characteristics of neoplasms, whether they are cancer cell biology, carcinogenesis mechanism, neoplasms of the maxillofacial system and sequels of antineoplastic treatments. In this context, methods have been developed that offer a better quality of life for patients diagnosed with this pathology, as well as preventive vaccine models that may, in the not too distant future, contribute to this goal to be successfully achieved.
KEY WORDS: genes, neoplasm, head and neck neoplasms, early detection of cancer, pathology, oral, dental research.
How to cite this article
MATOS, J. D. M.; NAKANO, L. J. N.; LOPES, G. R. S.; MAIS, S. E. S.; BARBOSA, A. B.; BOTTINO, M. A. & ANDRADE, V. C. Current insights on neoplasms and adequate dental care for patients with oral cancer. Int. J. odontostomat., 17(3):356-371, 2023.