Use of Chlorhexidine Bioadhesive Gel to Reduce Infection and Discomfort in Alveolar Bone Graft Wound: A Randomized Pilot Study

2022 • Volume 16 • Issue 3

Bernardo da Fonseca Orcina; Marcelo Medeiros Battistetti; Marina de Almeida Barbosa Mello; Renato Yassutaka Faria Yaedú & Paulo Sérgio da Silva Santos



The objective of this study was to analyze the inflammation index, edema, bacterial plaque presence and postoperative discomfort, with the use of chlorhexidine gel. This is a randomized double-blinded pilot study, with 21 unilateral cleft lip and palate individuals, randomized into 2 groups: Test Group (TG), with 7 individuals who used 0.2 % chlorhexidine bioadhesive gel in the surgical wound after the bone graft; and Control Group (CG) with 14 individuals who used a placebo gel as the same way. The gel was applied on the surgical wound suture after alveolar bone graft. The evaluation criteria of the gel application effectiveness were the visual analogue scale (VAS) for pain control and/or discomfort and clinical evaluation of inflammatory condition and/or wound infection. The study showed promising results for postoperatively use of the chlorhexidine gel, although there was no statistically significant difference between the groups.

KEY WORDS: chlorhexidine, dental plaque, bone transplantation.


How to cite this article

ORCINA, B. F.; BATTISTETTI, M. M.; MELLO, M. A. B.; YAEDÚ, R. Y. F. & DA SILVA SANTOS, P. S. Use of chlorhexidine bioadhesive gel to reduce infection and discomfort in alveolar bone graft wound: A randomized pilot study. Int. J. Odontostomat., 16(3):359-363, 2022.


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