Resistance of Staphylococcus aureus Strains Isolated from the Oral Mucosa in a Young Peruvian Population

2021 • Volume 15 • Issue 3

Alfredo Márquez-Oviedo; Ada Carolina Romero-Coasaca; Margarita F. Requena-Mendizábal; Elba MartínezCadillo; Ursula Mongrut-Villegas; Esperanza R. Ayón-Haro & Augusto S. Guardia-Huamaní



Staphylococcus aureus is an important pathogen responsible for a variety of infectious diseases. The increase of resistant strains is an issue of concern. There are very few studies reporting the resistant strains isolated from oral cavity. Aim: To determine the antimicrobial susceptibility of Staphylococcus aureus isolated from oral mucosa of Peruvian young healthy carriers. The study included 64 healthy individuals whose oral mucosa, nasal mucosa and hand swabs were collected and seeded in salt mannitol agar for primary isolation. Then, coagulase test was performed to confirm the presence of Staphylococcus aureus. After that, colonies of Staphylococcus aureus underwent antibiogram by using the Kirby Bauer method. The prevalence of Staphylococcus aureus positive strains isolated from oral mucosa, nasal mucosa, and hand, was 7.8 %, 15.6 %, 50.0 %, respectively. There was less than 40 % and 11 % of prevalence of susceptibility to erythromycin and penicillin, respectively, in the three studied samples. There was equal or more than 60% of prevalence of susceptibility to amoxicillin/clavulanic acid, cotrimoxazole, gentamicin, oxacillin, ciprofloxacin, vancomycin and ampicillin/sulbactam in all the studied samples. Vancomycin resistance was found in 10 – 20 % of all samples. A high prevalence in susceptibility to amoxicillin/clavulanic acid, gentamicin, co-trimoxazole, oxacillin, ciprofloxacin, vancomycin and ampicillin /sulbactam in healthy carriers was found. Vancomycin resistance percentage is higher than previous reports.

KEY WORDS: Staphylococcus aureus, microbial sensitivity tests, young adult.


How to cite this article

MÁRQUEZ-OVIEDO, A.; ROMERO-COASACA, A. C.; REQUENA-MENDIZÁBAL, M. F.; MARTÍNEZ-CADILLO, E.; MONGRUT-VILLEGAS, U.; AYÓN-HARO, E. R. & GUARDIA-HUAMANÍ, A. S. Resistance of Staphylococcus aureus strains isolated from the oral mucosa in a young Peruvian population. Int. J. Odontostomat., 15(3):634-638, 2021.


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