Denture stomatitis (DS) is a condition associated with the use of removable dentures. Its diagnosis is mainly clinical and based in recognition of their injuries, being the Newton’s one of the most accepted classifications. It stresses that the diagnosis should be confirmed by microscopic observation of Candida in oral samples. The aim of this study was to determine the species of Candida more frequent in the palatal mucosa and determine in vitro susceptibility to Nystatin and Fluconazole of these isolated strains. A total of 100 patients were examined by identifying the removable prosthesis presence or absence of DS according to the classification of Newton. Each patient had a complete sample of the area and palate was carried out microbiological examination. 75% of patients had abnormalities in the palate mucosa compatible with DS (33% presented DS type I, type II 42.7% and 24% Type III), while 25% filed a healthy mucosa. In 53.3% of patients with DS presented positive culture for Candida, only 16% had positive culture in the normal mucosa. The species of Candida albicans were the most frequently isolated (75%), followed by C. tropicallis (15%) and the rest of the crops were presented both species (10%). 100% of the strains were sensitive to Nistatina and Fluconazole, which was evidenced by the formation of inhibition area in yeast. There is a positive correlation between the DS and the presence of Candida, being C. albicans the kind who was isolated most frequently from the mucosa of patients with DS palate and healthy patients. All yeast were found susceptible to Nystatin and Fluconazole in vitro, demonstrating its effectiveness in Candida.
KEY WORDS: Denture stomatitis, dentures, Candida albicans, Nystatina, Fluconazole.
How to cite this article
BREVIS, A. P.; CANCINO, M. J. & CANTÍN, L. M. Denture stomatitis: a clinical and microbiological study of Candida. Int. J. Odontostomat., 2(1):101-108, 2008.